Characterizing International Classification of Disease ICDCM code validity is essential given widespread use of hospital discharge databases in research. A computer algorithm and physician reviewer classified definite and probable ischemic stroke, intracerebral hemorrhage ICH , and subarachnoid hemorrhage SAH.
Much epidemiologic research is based on estimation of an association between a putative risk factor and a health outcome—for example, plasma concentration of lipoproteins and ischemic heart disease. Since the repeatability of a risk factor measurement determines, in part, the ability to ascertain its association in populations, the Atheroscierosis Risk in Communities ARIC Intraindividual Variability Study was conducted to estimate various components of variation in analyte data and to estimate the repeatability of these measurements.
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